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Test Code PPMM Thiopurine Metabolites, Whole Blood

Important Note

6-Methylmercaptopurine Level (UNMC)

Additional Codes

Epic EAP Mayo Code
LAB4339 THIO


Ordering Guidance


This specimen cannot be shared with testing for tacrolimus, cyclosporine, sirolimus or everolimus. Testing for these must be ordered separately and separate specimens submitted.



Shipping Instructions


Specimen must be shipped refrigerated.



Specimen Required


Container/Tube: Lavender top (EDTA)

Specimen Volume: 3 mL

Collection Instructions: Send whole blood specimen in original tube. Do not aliquot, centrifuge, or freeze.


Useful For

Aids physicians in dose adjustments, minimizing dose-dependent toxicity, and monitoring compliance of thiopurine drug therapy

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

Thiopurine Metabolites, B

Specimen Type

Whole Blood EDTA

Specimen Minimum Volume

1.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Whole Blood EDTA Refrigerated (preferred) 8 days
  Ambient  24 hours

Reject Due To

Gross hemolysis Reject
Moderate hemolysis Reject
Gross lipemia OK
Gross icterus OK
Clotted Reject

Day(s) Performed

Monday, Wednesday, Friday

Report Available

2 to 4 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

80299

LOINC Code Information

Test ID Test Order Name Order LOINC Value
THIO Thiopurine Metabolites, B 82869-9

 

Result ID Test Result Name Result LOINC Value
49580 6-Thioguanine Nucleotides 32660-3
49581 6-Methylmercaptopurine 32654-6

Forms

If not ordering electronically, complete, print, and send Gastroenterology and Hepatology Test Request (T728) with the specimen