Test Code NSFIBM Nonalcoholic Steatohepatitis (NASH)-FibroTest, Serum and Plasma
Additional Codes
| EPIC EAP | Mayo |
| LAB6005 | NSFIB |
Ordering Guidance
This test is not offered for patients younger than 14 years of age. Testing will be canceled if a specimen is received from a patient in this age group.
Necessary Information
Age and sex are required.
Specimen Required
Both serum and plasma are required for this test.
Patient Preparation:
Fasting:12 hours, required
Specimen Type: Serum
Supplies: Amber Frosted Tube, 5 mL (T915)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Amber vial
Specimen Volume: 4 mL
Collection Instructions:
1. Centrifuge and aliquot serum into an amber vial within 2 hours of collection.
2. Centrifuged serum must be light protected within 4 hours of collection. It is acceptable to draw the blood and then protect it from light after centrifugation as long as it's within 4 hours of collection.
3. Label specimen as serum.
Specimen Type: Plasma
Collection Container/Tube: Gray top (potassium oxalate/sodium fluoride)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. Centrifuge and aliquot plasma into plastic vial.
2. Label specimen as plasma.
Forms
If not ordering electronically, complete, print, and send Gastroenterology and Hepatology Test Request (T728) with the specimen
Useful For
Diagnosis and the follow-up of liver fibrosis, steatosis, and inflammation
Estimating hepatic fibrosis
Assessing inflammation for metabolic diseases
Assessing severity of nonalcoholic steatohepatitis (NASH) in patients with nonalcoholic fatty liver disease with steatosis (NAFLD)
Assessing steatosis or fatty liver
Reassuring patients with steatosis only, without fibrosis
Managing patients with severe injuries such as advanced fibrosis and NASH
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| INTNS | NASH-FibroTest, Interpretation | No | Yes |
| APOAF | Apolipoprotein A1, S | No | Yes |
| A2MF | Alpha-2-Macroglobulin, S | Yes, (Order A2M) | Yes |
| HAPTF | Haptoglobin, S | Yes, (Order HAPT) | Yes |
| ALTF | Alanine Aminotransferase (ALT), S | Yes, (Order ALT) | Yes |
| GGTF | Gamma Glutamyltransferase (GGT), S | Yes, (Order GGT) | Yes |
| TBILF | Bilirubin, Total, S | Yes, (Order BILIT) | Yes |
| ASTF | Aspartate Aminotransferase (AST), S | Yes, (Order AST) | Yes |
| CHOLF | Cholesterol, Total, S | Yes, (Order CHOL) | Yes |
| TRIGF | Triglycerides, S | Yes, (Order TRIG) | Yes |
| GLURF | Glucose, Fasting, P | No | Yes |
Method Name
INTNS: Algorithm and Interpretation Provided through BioPredictive
APOAF: Automated Turbidimetric Immunoassay
A2MF, HAPTF: Nephelometry
ALTF: Photometric Rate, L-Alanine with Pyridoxal-5-Phosphate
GGTF: Photometric Rate
TBILF: Photometric, Diazonium Salt
ASTF: Photometric Rate, L-Aspartate with Pyridoxyl-5-Phosphate
CHOLF, TRIGF: Enzymatic Colorimetric
GLURF: Photometric, Hexokinase
Reporting Name
NASH-FibroTestSpecimen Type
Plasma NaFl-KOxSerum
Specimen Minimum Volume
Serum: 2 mL
Plasma: 0.25 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Plasma NaFl-KOx | Refrigerated (preferred) | 7 days | |
| Frozen | 14 days | ||
| Ambient | 7 days | ||
| Serum | Refrigerated (preferred) | 7 days | LIGHT PROTECTED |
| Frozen | 14 days | LIGHT PROTECTED | |
| Ambient | 24 hours | LIGHT PROTECTED |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
| Patients <14 years of age | Reject |
Day(s) Performed
Monday through Friday
Report Available
2 to 4 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
0003M
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| NSFIB | NASH-FibroTest | 93691-4 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| TBILF | Bilirubin, Total, S | 1975-2 |
| ALTF | Alanine Aminotransferase (ALT), S | 1743-4 |
| A2MF | Alpha-2-Macroglobulin, S | 1835-8 |
| APOAF | Apolipoprotein A1, S | 1869-7 |
| GGTF | Gamma Glutamyltransferase (GGT), S | 2324-2 |
| HAPTF | Haptoglobin, S | 46127-7 |
| GLURF | Glucose, Fasting, P | 1558-6 |
| TRIGF | Triglycerides, S | 2571-8 |
| CHOLF | Cholesterol, Total, S | 2093-3 |
| ASTF | Aspartate Aminotransferase (AST), S | 30239-8 |
| SCRF | FibroTest Score | 48795-9 |
| STGF | FibroTest Stage | 48794-2 |
| INTEF | FibroTest Interpretation | 88447-8 |
| SCRN2 | NashTest 2 Score | 93692-2 |
| GRDN | NashTest 2 Grade | 93693-0 |
| INTEN | NashTest 2 Interpretation | 93694-8 |
| SCRS2 | SteatoTest 2 Score | 93695-5 |
| GRDS | SteatoTest 2 Grade | 93696-3 |
| INTEI | SteatoTest 2 Interpretation | 93697-1 |
| CMMS | NASH-FibroTest Comment | 48767-8 |
| NUM | BioPredictive Serial Number | 74715-4 |