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Test Code NSFIBM Nonalcoholic Steatohepatitis (NASH)-FibroTest, Serum and Plasma

Additional Codes

EPIC EAP  Mayo
LAB6005 NSFIB


Ordering Guidance


This test is not offered for patients younger than 14 years of age. Testing will be canceled if a specimen is received from a patient in this age group.



Necessary Information


Age and sex are required.



Specimen Required


Both serum and plasma are required for this test.

 

Patient Preparation:

Fasting:12 hours, required

 

Specimen Type: Serum

Supplies: Amber Frosted Tube, 5 mL (T915)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Amber vial

Specimen Volume: 4 mL

Collection Instructions:

1. Centrifuge and aliquot serum into an amber vial within 2 hours of collection.

2. Centrifuged serum must be light protected within 4 hours of collection. It is acceptable to draw the blood and then protect it from light after centrifugation as long as it's within 4 hours of collection.

3. Label specimen as serum.

 

Specimen Type: Plasma

Collection Container/Tube: Gray top (potassium oxalate/sodium fluoride)

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Centrifuge and aliquot plasma into plastic vial.

2. Label specimen as plasma.


Forms

If not ordering electronically, complete, print, and send Gastroenterology and Hepatology Test Request (T728) with the specimen

Useful For

Diagnosis and the follow-up of liver fibrosis, steatosis, and inflammation

 

Estimating hepatic fibrosis

 

Assessing inflammation for metabolic diseases

 

Assessing severity of nonalcoholic steatohepatitis (NASH) in patients with nonalcoholic fatty liver disease with steatosis (NAFLD)

 

Assessing steatosis or fatty liver

 

Reassuring patients with steatosis only, without fibrosis

 

Managing patients with severe injuries such as advanced fibrosis and NASH

Profile Information

Test ID Reporting Name Available Separately Always Performed
INTNS NASH-FibroTest, Interpretation No Yes
APOAF Apolipoprotein A1, S No Yes
A2MF Alpha-2-Macroglobulin, S Yes, (Order A2M) Yes
HAPTF Haptoglobin, S Yes, (Order HAPT) Yes
ALTF Alanine Aminotransferase (ALT), S Yes, (Order ALT) Yes
GGTF Gamma Glutamyltransferase (GGT), S Yes, (Order GGT) Yes
TBILF Bilirubin, Total, S Yes, (Order BILIT) Yes
ASTF Aspartate Aminotransferase (AST), S Yes, (Order AST) Yes
CHOLF Cholesterol, Total, S Yes, (Order CHOL) Yes
TRIGF Triglycerides, S Yes, (Order TRIG) Yes
GLURF Glucose, Fasting, P No Yes

Method Name

INTNS: Algorithm and Interpretation Provided through BioPredictive

APOAF: Automated Turbidimetric Immunoassay

A2MF, HAPTF: Nephelometry

ALTF: Photometric Rate, L-Alanine with Pyridoxal-5-Phosphate

GGTF: Photometric Rate

TBILF: Photometric, Diazonium Salt

ASTF: Photometric Rate, L-Aspartate with Pyridoxyl-5-Phosphate

CHOLF, TRIGF: Enzymatic Colorimetric

GLURF: Photometric, Hexokinase

Reporting Name

NASH-FibroTest

Specimen Type

Plasma NaFl-KOx
Serum

Specimen Minimum Volume

Serum: 2 mL
Plasma: 0.25 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma NaFl-KOx Refrigerated (preferred) 7 days
  Frozen  14 days
  Ambient  7 days
Serum Refrigerated (preferred) 7 days LIGHT PROTECTED
  Frozen  14 days LIGHT PROTECTED
  Ambient  24 hours LIGHT PROTECTED

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject
Patients <14 years of age Reject

Day(s) Performed

Monday through Friday

Report Available

2 to 4 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

0003M

LOINC Code Information

Test ID Test Order Name Order LOINC Value
NSFIB NASH-FibroTest 93691-4

 

Result ID Test Result Name Result LOINC Value
TBILF Bilirubin, Total, S 1975-2
ALTF Alanine Aminotransferase (ALT), S 1743-4
A2MF Alpha-2-Macroglobulin, S 1835-8
APOAF Apolipoprotein A1, S 1869-7
GGTF Gamma Glutamyltransferase (GGT), S 2324-2
HAPTF Haptoglobin, S 46127-7
GLURF Glucose, Fasting, P 1558-6
TRIGF Triglycerides, S 2571-8
CHOLF Cholesterol, Total, S 2093-3
ASTF Aspartate Aminotransferase (AST), S 30239-8
SCRF FibroTest Score 48795-9
STGF FibroTest Stage 48794-2
INTEF FibroTest Interpretation 88447-8
SCRN2 NashTest 2 Score 93692-2
GRDN NashTest 2 Grade 93693-0
INTEN NashTest 2 Interpretation 93694-8
SCRS2 SteatoTest 2 Score 93695-5
GRDS SteatoTest 2 Grade 93696-3
INTEI SteatoTest 2 Interpretation 93697-1
CMMS NASH-FibroTest Comment 48767-8
NUM BioPredictive Serial Number 74715-4