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Test Code NMS1M Necrotizing Myopathy Evaluation, Serum

Additional Codes

EPIC EAP  Mayo
LAB3485 NMS1


Ordering Guidance


Before ordering this test, assess the probability of the patient having immune-mediated necrotizing myopathy by using the Immune-mediated necrotizing myopathy calculator.



Necessary Information


Provide the following information:

-Relevant clinical information

-Ordering provider name, phone number, mailing address, and e-mail address



Specimen Required


Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 3 mL

Collection Instructions: Centrifuge within 2 hours of collection and aliquot serum into a plastic vial.


Useful For

Evaluating patients with suspected necrotizing autoimmune myopathy

Profile Information

Test ID Reporting Name Available Separately Always Performed
NSI1 Necrotizing Myopathy Interp, S No Yes
HMGCR HMG-CoA Reductase Ab, S Yes Yes
SRPIS SRP IFA Screen, S No Yes

Method Name

SRPIS, SRPTS: Indirect Immunofluorescence Assay (IFA)

SRPBS: Immunoblot

HMGCR: Chemiluminescent Assay (CIA)

NSI1: Medical Interpretation

Reporting Name

Necrotizing Myopathy Evaluation, S

Specimen Type

Serum

Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  72 hours

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Day(s) Performed

Tuesday, Thursday

 

Report Available

10 to 14 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

86255

82397

86256 (if appropriate)

84182 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
NMS1 Necrotizing Myopathy Evaluation, S 97561-5

 

Result ID Test Result Name Result LOINC Value
607414 HMG-CoA Reductase Ab, S 93493-5
603543 Necrotizing Myopathy Interp, S 69048-7
603540 SRP IFA Screen, S 97562-3

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
SRPBS SRP Immunoblot, S No No
SRPTS SRP IFA Titer, S No No

Forms

If not ordering electronically, complete, print, and send a Neurology Specialty Testing Client Test Request (T732) with the specimen.