Home
HelpTest Code META3 Metanephrines with 3-Methoxytyramine, 24 Hour, Urine
Additional Codes
| Hospital Order Code |
| Lab2608 MISMGO |
Ordering Guidance
Necessary Information
24-Hour volume (in milliliters) is required.
Specimen Required
Patient Preparation: Tricyclic antidepressants, labetalol, and sotalol medications may elevate levels of metanephrines producing results that cannot be interpreted. If clinically feasible, it is optimal to discontinue these medications at least 1 week before collection. For advice on assessing the risk of removing patients from these medications and alternatives, consider consultation with a specialist in endocrinology or hypertension.
Supplies: Urine Tubes, 10 mL (T068)
Submission Container/Tube: Plastic urine tube
Specimen Volume: 10 mL
Collection Instructions:
1. Complete 24-hour urine collections are preferred, especially for patients with episodic hypertension; ideally the collection should begin at the onset of a "spell."
2. Add 10 g (pediatric: 3 g) of boric acid or 25 mL (pediatric: 15 mL) of 50% acetic acid as preservative at start of collection.
3. Collect urine for 24 hours.
Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collections.
Useful For
A first- and second-tier screening test for the presumptive diagnosis of catecholamine-secreting pheochromocytomas and paragangliomas
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| 3MT1 | 3-Methoxytyramine, U | Yes, (Order 3MT) | Yes |
| METAF | Metanephrines, Fractionated, 24h, U | Yes | Yes |
Special Instructions
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Metanephrines with 3-MT, 24h, USpecimen Type
UrineSpecimen Minimum Volume
4 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Urine | Refrigerated (preferred) | 28 days |
| Frozen | 28 days | |
| Ambient | 21 days |
Reject Due To
| Gross hemolysis | OK |
| Gross icterus | OK |
Day(s) Performed
Monday through Friday
Report Available
3 to 5 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
82542
83835
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| META3 | Metanephrines with 3-MT, 24h, U | 101400-0 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 8552 | Metanephrine, U | 104629-1 |
| 609422 | 3-Methoxytyramine, U | 32618-1 |
| 21545 | Normetanephrine, U | 104631-7 |
| 83006 | Total Metanephrines, U | 104630-9 |
| TM50 | Collection Duration (h) | 13362-9 |
| VL48 | Volume (mL) | 3167-4 |
| 2434 | Comment | 48767-8 |