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Test Code LAMOTM Lamotrigine, Serum

Additional Codes

EPIC EAP  Mayo
LAB475 LAMO

 

Reporting Name

Lamotrigine, S

Useful For

Monitoring serum concentration of lamotrigine

 

Assessing compliance

 

Adjusting lamotrigine dose in patients receiving other anticonvulsant drugs that interact pharmacokinetically with lamotrigine

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Collect blood immediately before next scheduled dose.

2. Only for sustained-release formulations, collect blood a minimum of 12 hours after last dose.

3. Within 2 hours of collection, centrifuge.

4. For red-top tubes, immediately aliquot serum into a plastic vial.

5. For serum gel tubes, the serum must be aliquoted into a plastic vial within 24 hours of collection.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK
 

Reference Values

Patients receiving therapeutic doses usually have lamotrigine concentrations of 3.0-15.0 mcg/mL.

Day(s) Performed

Monday through Sunday

CPT Code Information

80175

LOINC Code Information

Test ID Test Order Name Order LOINC Value
LAMO Lamotrigine, S 6948-4

 

Result ID Test Result Name Result LOINC Value
80999 Lamotrigine, S 6948-4

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

Report Available

Same day/1 to 2 days

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-Neurology Specialty Testing Client Test Request (T732)

-General Request (T239)

-Therapeutics Test Request (T831)