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Test Code HOLDF Hematologic Disorders, Fluorescence In Situ Hybridization (FISH) Hold, Varies

Additional Codes

Hospital Order Code
Lab2608   MISMGO

Useful For

Processing the bone marrow or peripheral blood specimen but delaying fluorescence in situ hybridization analysis while preliminary morphologic assessment is in process

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
AMLFA Adult-AML panel, FISH Yes No
AMLMF AML, Specified FISH Yes No
AMLFP Pediatric-AML panel, FISH Yes No
BALAF Adult ALL (B-cell), FISH Yes No
BALMF ALL (B-cell), Specified FISH Yes No
BALFP Pediatric B-ALL/LBL panel, FISH Yes No
BLPMF B-cell Lymphoma, Specified FISH Yes No
CLLDF CLL, Diagnostic FISH Yes No
CLLMF CLL, Specified FISH Yes No
COGBF COG, ALL (B-cell), FISH Yes No
COGMF COG, AML, FISH Yes No
COGTF COG, ALL (T-cell), FISH Yes No
EOSFD Chronic Eosinophilia pnl, Diag FISH Yes No
EOSMF Chronic Eosinophilia, Spec FISH Yes No
HEMMF Hematologic Specified FISH Yes No
MDSDF MDS, Diagnostic FISH Yes No
MDSMF MDS, Specified FISH Yes No
MFCDF Myeloma Fixed Cell, High Risk, FISH Yes No
PHLFD BCR/ABL1-like B-ALL pnl, Diag, FISH Yes No
TALAF Adult ALL (T-cell), FISH Yes No
TALMF ALL (T-cell), Specified FISH Yes No
TALFP Pediatric T-ALL/LBL panel, FISH Yes No
TLPFD T-lymphoma BM/BL panel, Diag, FISH Yes No
TLPMF T-cell Lymphoma B/BM, Spec FISH Yes No

Method Name

Direct Preparation of Specimen

Reporting Name

Heme FISH Hold, B/BM

Specimen Type

Varies


Ordering Guidance


This test is designed to hold blood and bone marrow specimens for fluorescence in situ hybridization testing only.

 

This test does not apply to chromosome analysis. If specimen is to be held for chromosome analysis, order HOLDC / Hematologic Disorders, Chromosome Hold, Varies.

 

Due to stability issues, test PCPDS / Plasma Cell Proliferative Disorder, High-Risk with Reflex Probes, Diagnostic FISH Evaluation, Bone Marrow cannot be added onto specimens held under this test.



Shipping Instructions


Advise Express Mail or equivalent if not on courier service.



Necessary Information


1. A reason for testing must be provided. If this information is not provided, an appropriate indication for testing may be entered by Mayo Clinic Laboratories.

2. A flow cytometry and/or bone marrow pathology report should be submitted with each specimen. The laboratory will not reject testing if this information is not provided, but appropriate testing and interpretation may be compromised or delayed.



Specimen Required


Submit only 1 of the following specimens:

 

Preferred:

Specimen Type: Bone marrow

Container/Tube:

Preferred: Yellow top (ACD)

Acceptable: Green top (sodium heparin) or lavender top (EDTA)

Specimen Volume: 2 to 3 mL

Collection Instructions:

1. It is preferable to send the first aspirate from the bone marrow collection.

2. Invert several times to mix bone marrow.

3. Send bone marrow in original tube. Do not aliquot.

 

Acceptable:

Specimen Type: Whole Blood

Container/Tube:

Preferred: Yellow top (ACD)

Acceptable: Green top (sodium heparin) or lavender top (EDTA)

Specimen Volume: 6 mL

Collection Instructions:

1. Invert several times to mix blood.

2. Send whole blood in original tube. Do not aliquot.


Specimen Minimum Volume

Bone marrow: 1 mL; Whole blood: 2 mL

Specimen Stability Information

Specimen Type Temperature Time
Varies Ambient (preferred)
  Standard 

Reject Due To

Fresh tissue Reject

Day(s) Performed

Monday through Friday

Report Available

4 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

See individual reflex tests

LOINC Code Information

Result ID Test Result Name Result LOINC Value
51836 Result Summary 50397-9
51838 Interpretation 69965-2
CG666 Reason for Referral 42349-1
CG667 Specimen 31208-2
51839 Source 31208-2
CG791 Requested FISH Test 48767-8
51841 Method 85069-3
53433 Additional Information 48767-8
51842 Released by 18771-6

Forms

If not ordering electronically, complete, print, and send a Hematopathology/Cytogenetics Test Request (T726) with the specimen.

Test Classification

Not Applicable