Useful For

As part of the diagnosis and workup of precocious and delayed puberty in females and, to a lesser degree, males

As part of the diagnosis and workup of suspected disorders of sex steroid metabolism (eg, aromatase deficiency and 17 alpha-hydroxylase deficiency)

As an adjunct to clinical assessment, imaging studies and bone mineral density measurement in the fracture risk assessment of postmenopausal women, and, to a lesser degree, older men

Monitoring low-dose female hormone replacement therapy in postmenopausal women

Monitoring antiestrogen therapy (eg, aromatase inhibitor therapy)