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Test Code EBVBAT Epstein-Barr Virus (EBV) Antibody Profile

Important Note

Includes EBV AB Panel and Viral Capsid Antigen (VCA) IgG & IgM

Additional Codes

Hospital Ordering Code

LAB5480  Epstein-Barr Virus Antibody Profile

Specimen Requirements

Preferred Collection Container: 

SST (Serum Separator)
Light Green (Lithium Heparin Plasma Separator Tube)

 

Also Acceptable Collection Container: 

Red (No Additive)
Green No Gel (Lithium Heparin)

 

Collection Information: 

Collect blood in a serum separator tube or Light Green (Lithium Heparin Plasma Separator Tube).

 

Transport Information: 

Centrifuge and aliquot 1.0 mL of serum into a plastic transport vial. Send refrigerated.

 

Minimum Sample Volume: 

0.25 mL of serum (approximately 0.5 mL of whole blood based upon a normal patient hematocrit)

 

Unacceptable Conditions: 

Gross hemolysis

Stability

Refrigerated Stability: 

7 days

 

Frozen Stability: 

Indefinitely

Performing Laboratory

Pathology Laboratory, UnityPoint Health, Des Moines

CPT

86664 EBNA

86665 x2 VCA, IgG & IgM

Methodology

Multiplex Flow Immunoassay (MFI)

Performance

Daily

 

Analytical Time: 

1 day

 

Testing Laboratory: 

Pathology Laboratory

 

Laboratory Section: 

Core Laboratory

Alias

Anti EBV Serology, E. B. (Epstein-Barr) Virus, EBNA (Epstein-Barr Nuclear Antigen), EBV (Epstein-Barr Virus) Battery, EBV (Epstein-Barr Virus) Panel, EBV (Epstein-Barr Virus), EBV Panel, Serum, Epstein Barr Virus, Epstein-Barr Virus AB, Epstein-Barr Virus Battery, Epstein-Barr Virus Panel, VCA (Viral Capsid Antigen) IgG and IgM, Viral Capsid Antigen (VCA) Titer, Infectious Mononucleosis, EBV Ab, Serum

Interpretive Data

Antibody Timing of when the antibody is typically detected in the blood
Viral Capsid Antigen (VCA)-IgM antibody Appears first after exposure to the virus and then tends to disappear after about 4 to 6 weeks
VCA-IgG antibody Emerges during acute infection with the highest level at 2 to 4 weeks, then drops slightly, stabilizes, and is present for life
Early Antigen (EA-D) antibody Appears during the acute infection phase and then tends to disappear; about 20% of those infected will continue to have detectable quantities for several years after the EBV infection has resolved.
Epstein-Barr Nuclear Antigen (EBNA) antibody Does not usually appear until the acute infection has resolved; it develops about 2 to 4 months after the initial infection and is then is present for life.