Test Code EBVBAT Epstein-Barr Virus (EBV) Antibody Profile
Additional Codes
| Hospital Ordering Code |
|---|
|
LAB5480 Epstein-Barr Virus Antibody Profile |
Specimen Requirements
Preferred Collection Container:
SST (Serum Separator)
Light Green (Lithium Heparin Plasma Separator Tube)
Also Acceptable Collection Container:
Red (No Additive)
Green No Gel (Lithium Heparin)
Collection Information:
Collect blood in a serum separator tube or Light Green (Lithium Heparin Plasma Separator Tube).
Transport Information:
Centrifuge and aliquot 1.0 mL of serum into a plastic transport vial. Send refrigerated.
Minimum Sample Volume:
0.25 mL of serum (approximately 0.5 mL of whole blood based upon a normal patient hematocrit)
Unacceptable Conditions:
Gross hemolysis
Stability
Refrigerated Stability:
7 days
Frozen Stability:
Indefinitely
Performing Laboratory
Pathology Laboratory, UnityPoint Health, Des Moines
CPT
86664 EBNA
86665 x2 VCA, IgG & IgM
Methodology
Multiplex Flow Immunoassay (MFI)
Performance
Daily
Analytical Time:
1 day
Testing Laboratory:
Pathology Laboratory
Laboratory Section:
Core Laboratory
Alias
Anti EBV Serology, E. B. (Epstein-Barr) Virus, EBNA (Epstein-Barr Nuclear Antigen), EBV (Epstein-Barr Virus) Battery, EBV (Epstein-Barr Virus) Panel, EBV (Epstein-Barr Virus), EBV Panel, Serum, Epstein Barr Virus, Epstein-Barr Virus AB, Epstein-Barr Virus Battery, Epstein-Barr Virus Panel, VCA (Viral Capsid Antigen) IgG and IgM, Viral Capsid Antigen (VCA) Titer, Infectious Mononucleosis, EBV Ab, Serum
Interpretive Data
| Antibody | Timing of when the antibody is typically detected in the blood |
| Viral Capsid Antigen (VCA)-IgM antibody | Appears first after exposure to the virus and then tends to disappear after about 4 to 6 weeks |
| VCA-IgG antibody | Emerges during acute infection with the highest level at 2 to 4 weeks, then drops slightly, stabilizes, and is present for life |
| Early Antigen (EA-D) antibody | Appears during the acute infection phase and then tends to disappear; about 20% of those infected will continue to have detectable quantities for several years after the EBV infection has resolved. |
| Epstein-Barr Nuclear Antigen (EBNA) antibody | Does not usually appear until the acute infection has resolved; it develops about 2 to 4 months after the initial infection and is then is present for life. |