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Test Code EBVBAT Epstein-Barr Virus (EBV) Antibody Profile

Important Note

Includes EBV AB Panel and Viral Capsid Antigen (VCA) IgG & IgM

Additional Codes

Hospital Ordering Code

LAB5480  Epstein-Barr Virus Antibody Profile

Specimen Requirements

Preferred Collection Container: 

SST (Serum Separator)
Light Green (Lithium Heparin Plasma Separator Tube)

 

Also Acceptable Collection Container: 

Red (No Additive)
Green No Gel (Lithium Heparin)

 

Collection Information: 

Collect blood in a serum separator tube or Light Green (Lithium Heparin Plasma Separator Tube).

 

Transport Information: 

Centrifuge and aliquot 1.0 mL of serum into a plastic transport vial. Send refrigerated.

 

Minimum Sample Volume: 

0.25 mL of serum (approximately 0.5 mL of whole blood based upon a normal patient hematocrit)

 

Unacceptable Conditions: 

Gross hemolysis

Stability

Refrigerated Stability: 

7 days

 

Frozen Stability: 

Indefinitely

CPT

86664 EBNA

86665 x2 VCA, IgG & IgM

Performing Laboratory

Pathology Laboratory, UnityPoint Health, Des Moines

Methodology

Multiplex Flow Immunoassay (MFI)

Alias

Anti EBV Serology, E. B. (Epstein-Barr) Virus, EBNA (Epstein-Barr Nuclear Antigen), EBV (Epstein-Barr Virus) Battery, EBV (Epstein-Barr Virus) Panel, EBV (Epstein-Barr Virus), EBV Panel, Serum, Epstein Barr Virus, Epstein-Barr Virus AB, Epstein-Barr Virus Battery, Epstein-Barr Virus Panel, VCA (Viral Capsid Antigen) IgG and IgM, Viral Capsid Antigen (VCA) Titer, Infectious Mononucleosis, EBV Ab, Serum

Performance

Daily

 

Analytical Time: 

1 day

 

Testing Laboratory: 

Pathology Laboratory

 

Laboratory Section: 

Core Laboratory

Interpretive Data

Antibody Timing of when the antibody is typically detected in the blood
Viral Capsid Antigen (VCA)-IgM antibody Appears first after exposure to the virus and then tends to disappear after about 4 to 6 weeks
VCA-IgG antibody Emerges during acute infection with the highest level at 2 to 4 weeks, then drops slightly, stabilizes, and is present for life
Early Antigen (EA-D) antibody Appears during the acute infection phase and then tends to disappear; about 20% of those infected will continue to have detectable quantities for several years after the EBV infection has resolved.
Epstein-Barr Nuclear Antigen (EBNA) antibody Does not usually appear until the acute infection has resolved; it develops about 2 to 4 months after the initial infection and is then is present for life.