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Test Code CDIFS Clostridioides difficile Culture with Antimicrobial Susceptibilities, Varies


Ordering Guidance


Culture is not the preferred diagnostic test for Clostridioides difficile. For routine diagnostic testing, order CDPCR / Clostridioides difficile Toxin, PCR, Feces



Necessary Information


Specimen source is required.



Specimen Required


Submit only 1 of the following specimens:

 

Patient Preparation: Patient should not use antacids, barium, bismuth, antidiarrheal medication, zinc oxide paste, Vagisil cream or oily laxatives prior to specimen collection.

 

Preferred:

Specimen Type: Preserved feces

Supplies:

-Culture and Sensitivity Stool Transport Vial (T058)

-Stool Collection Kit, Random (T635)

Container/Tube: Commercially available transport system specific for recovery of enteric pathogens from fecal specimens (15 mL of non-nutritive transport medium containing phenol red as a pH indicator, either Cary-Blair or Para-Pak C and S [T058])

Specimen Volume: Representative portion of feces; 5 mL

Collection Instructions:

1. Collect fresh feces and submit 1 gram or 5 mL in container with transport medium.

2. Within 2 hours of collection, place feces in preservative.

Specimen Stability Information: Ambient (preferred) 96 hours/Refrigerated 96 hours/Frozen 7 days

Additional Information: Only diarrheal (ie., unformed) feces should be tested. Testing formed feces for Clostridioides difficile is not clinically indicated.

 

Acceptable:

Specimen Type: Unpreserved feces

Supplies:

-Stool container, Small (Random), 4 oz (T288)

-Stool Collection Kit, Random (T635)

Container/Tube: Stool container

Specimen Volume: Representative portion of stool

Collection Instructions: Collect fresh stool and submit representative sample in stool container.

Specimen Stability Information: Ambient (preferred) 72 hours/Frozen 7 days

Additional Information: Only diarrheal (i.e., unformed) stool should be tested. Testing formed stool for Clostridioides difficile is not clinically indicated.

 

Specimen Type: Fresh tissue or biopsy

Sources: Colon

Supplies: Anaerobe Transport Tube (T588)

Specimen Volume: Entire collection, 1 to 2 cm(3)

Collection Instructions: Aseptically collect 1 to 2 cm(3) piece of tissue whenever possible. In general, a larger piece of tissue is preferred. Submit in an anaerobic transport tube.

Specimen Stability Information: Ambient 72 hours


Useful For

Providing an isolate suitable for antimicrobial susceptibility testing to direct antimicrobial therapy of extraluminal infections and in cases of treatment failure

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
ANAID Anaerobe Ident No, (Bill Only) No
RMALA Id MALDI-TOF Mass Spec Anaerobe No, (Bill Only) No
ISAN Anaerobe Ident by Sequencing No, (Bill Only) No
SANA Anaerobe Suscep per agent No, (Bill Only) No
BATTA Anaerobe Suscep Battery No, (Bill Only) No

Special Instructions

Method Name

Conventional Culture Technique with Minimal Inhibitory Concentration (MIC) by Agar Dilution

Reporting Name

C. difficile Culture + Susc

Specimen Type

Varies

Specimen Minimum Volume

Stool: 1 gram or 5 mL; Tissue: 5 mm(3)

Specimen Stability Information

Specimen Type Temperature Time
Varies Varies

Reject Due To

Fecal swab Reject
Specimen in Ecofix Reject

Day(s) Performed

Monday through Sunday

Report Available

2 to 9 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

87081-C. difficile Culture

87076-Anaerobe Ident (if appropriate)

87076-Id MALDI-TOF Mass Spec Anaerobe (if appropriate)

87153-Anaerobe Ident by Sequencing (if appropriate)

87181-Anaerobe Susceptibility per agent (if appropriate)

87181 x 3-Antimicrobial Susceptibility, Anaerobic Bacteria, MIC (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CDIFS C. difficile Culture + Susc 105047-5

 

Result ID Test Result Name Result LOINC Value
CDIFS C. difficile Culture + Susc 105047-5