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Test Code AGAS Alpha-Galactosidase, Serum

Additional Codes

Hospital Order Code
Lab2608   MISMGO

 

Reporting Name

Alpha-Galactosidase, S

Useful For

Diagnosis of Fabry disease in male patients

 

Preferred screening test (serum) for Fabry disease

 

This test is not useful for patients undergoing a work up for a meat or meat-derived product allergy.

Method Name

Fluorometric

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum


Ordering Guidance


If testing is needed for assessment of meat or meat-derived product allergy, order either ALGAL / Galactose-Alpha-1,3-Galactose (Alpha-Gal), IgE, Serum or APGAL / Galactose-Alpha-1,3-Galactose (Alpha-Gal) Mammalian Meat Allergy Profile, Serum.

 

Enzyme testing is unreliable for female patients as results may be within the normal values even in affected female patients; order GLA / Fabry Disease, GLA Gene Sequencing with Deletion/Duplication, Varies.



Additional Testing Requirements


Urine sediment analysis for the accumulating trihexoside substrate and measurement of globotriaosylsphingosine are recommended. Order both CTSU / Ceramide Trihexosides and Sulfatides, Random, Urine and LGB3S / Globotriaosylsphingosine, Serum in conjunction with this test.



Necessary Information


Sex of patient is required for interpretation of results.



Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL serum

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

Serum: 0.3 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Frozen (preferred) 14 days
  Refrigerated  24 hours

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Day(s) Performed

Tuesday, Friday

CPT Code Information

82657

LOINC Code Information

Test ID Test Order Name Order LOINC Value
AGAS Alpha-Galactosidase, S 1813-5

 

Result ID Test Result Name Result LOINC Value
50590 Alpha-Galactosidase,S 1813-5
50584 Interpretation 59462-2
50586 Reviewed By 18771-6

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

Report Available

2 to 5 days

Forms

1. New York Clients-Informed consent is required. Document on the request form or electronic order that a copy is on file. The following documents are available:

-Informed Consent for Genetic Testing (T576)

-Informed Consent for Genetic Testing-Spanish (T826)

2. Biochemical Genetics Patient Information (T602)

3. If not ordering electronically, complete, print, and send a Biochemical Genetics Test Request (T798) with the specimen.