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HelpTest Code 17PRN Pregnenolone and 17-Hydroxypregnenolone, Serum
Additional Codes
| Hospital Order Code |
| Lab2608 MISMGO |
Reporting Name
Pregnenolone and 17-OH PregnenoloneUseful For
An ancillary test for congenital adrenal hyperplasia (CAH), particularly in situations in which a diagnosis of both 21- and 11-hydroxylase deficiency have been ruled out
Confirming a diagnosis of 3-beta-hydroxysteroid dehydrogenase deficiency and 17-alpha-hydroxylase deficiency
As part of a battery of tests to evaluate women with hirsutism or infertility; both can result from adult-onset CAH
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| PREGN | Pregnenolone, S | Yes | Yes |
| 17OHP | 17-Hydroxypregnenolone, S | Yes | Yes |
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Portions of this test are covered by patents held by Quest Diagnostics
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Frozen | 28 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Special Instructions
Day(s) Performed
Monday, Wednesday, Friday
CPT Code Information
84140-Pregnenolone
84143-17-Hydroxypregnenolone
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| 17PRN | Pregnenolone and 17-OH Pregnenolone | In Process |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 81151 | 17-Hydroxypregnenolone, S | 6765-2 |
| 88645 | Pregnenolone, S | 2837-3 |