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Test Code 17OHP 17-Hydroxypregnenolone, Serum

Reporting Name

17-Hydroxypregnenolone, S

Useful For

As an ancillary test for congenital adrenal hyperplasia (CAH), particularly in situations in which a diagnosis of both 21- and 11-hydroxylase deficiency have been ruled out

 

Confirming a diagnosis of 3-beta-hydroxysteroid dehydrogenase deficiency

 

As part of a battery of tests to evaluate women with hirsutism or infertility; both can result from adult-onset CAH

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Frozen (preferred) 28 days
  Refrigerated  28 days

Special Instructions

Day(s) Performed

Monday, Wednesday, Friday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

84143

LOINC Code Information

Test ID Test Order Name Order LOINC Value
17OHP 17-Hydroxypregnenolone, S 6765-2

 

Result ID Test Result Name Result LOINC Value
81151 17-Hydroxypregnenolone, S 6765-2

Report Available

3 to 7 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)